Message by the Director of the Department of Immunization, Vaccines and Biologicals at WHO - April 2023

2023年4月-世界卫生组织免疫、疫苗和生物制品部主任致辞

We are pleased to have successfully concluded our 1st SAGE meeting of 2023 in March with deepest appreciation to our scientific experts, partners and immunization Regional Advisers.

我们很高兴 2023 年第一次SAGE大会于 3 月圆满结束，并向我们的科学专家、合作伙伴和免疫区域顾问致以最深切的谢意。

The recovery of the immunization programme in the wake of the pandemic impacts continues to dominate our focused efforts. This was a major topic at our 1st meeting of 2023 of the Strategic Advisory Group of Experts on Immunization (SAGE) in March and was a theme of the Global Vaccine and Immunization Research Forum (GVIRF) biannual convening in Seoul, South Korea in April. These two major convenings, on policy and research, were at the heart of the collective early 2023 discussions and forward momentum. I want to express deep appreciation to the scientific experts, partners, and to the WHO Regional Advisors on Immunization, for the participation in both of these major convenings. The opportunities we have, collectively, to forge the way toward more impactful programmes, and advance the research agenda on the most meaningful issues set the foundations for what will be better vaccines and immunization programmes around the corner.

疫情影响后免疫方案的恢复继续主导着我们的重点努力。这是3月份免疫专家战略咨询小组（SAGE）2023年第一次会议的主要议题，也是4月份在韩国首尔召开的一年两次的全球疫苗和免疫研究论坛（GVIRF）的主题。关于政策和研究的这两次主要会议是2023年初集体讨论和前进势头的核心。我要对科学专家、合作伙伴和世界卫生组织地区免疫顾问参加这两次重要会议深表感谢。我们有机会共同打造更有影响力的项目，并推进最有意义问题的研究议程，为即将到来的更好的疫苗和免疫项目奠定基础。

Among the numerous recommendations, the SAGE issued recommendations focusing on the need for immunization intensification, including catch-up activities, and for enhancing preparedness for outbreak response, with Regions supporting high-risk countries. It was agreed that the highest priorities for the 2023-2025 period will be the zero-dose child agenda, routine immunization strengthening (with gap filling to reduce outbreak risk especially of measles and polio), response to outbreaks, revitalization of HPV vaccination, malaria vaccine introduction, and integration of COVID-19 vaccination into routine immunization and primary health care. SAGE also issued a major update to the Roadmap for Prioritizing Uses of COVID-19 Vaccine which takes into account the current disease epidemiology, the characteristics of the Omicron variant, and the evidence on high population immunity across all geographies (derived from a combination of infection and vaccine induced immunity). This critically important resource will be valuable to countries as they determine national immunization recommendations in the transition from the acute phase of the pandemic toward COVID-19 vaccine programmes that are integrated into routine immunization and other primary health care services. Please click here to view to the full SAGE report.

在众多建议中，专家咨询小组提出的建议侧重于加强免疫接种的必要性，包括追赶活动，以及加强疫情应对的准备，各区域支持高风险国家。与会者一致认为，2023-2025年期间的最高优先事项将是零剂量儿童议程、加强常规免疫接种（填补空白以降低疫情风险，特别是麻疹和脊髓灰质炎）、应对疫情、振兴人乳头瘤病毒疫苗接种、引入疟疾疫苗以及将新冠肺炎疫苗接种纳入常规免疫接种和初级卫生保健。SAGE还发布了对新冠肺炎疫苗优先使用路线图的重大更新，该更新考虑了当前的疾病流行病学、奥密克戎变异体的特征以及所有地区高人群免疫力的证据（来自感染和疫苗诱导免疫的组合）。这一至关重要的资源对各国来说将是宝贵的，因为它们在从疫情急性期向纳入常规免疫接种和其他初级卫生保健服务的新冠肺炎疫苗方案过渡的过程中确定了国家免疫接种建议。请点击此处查看完整的SAGE报告。

The 4th biannual Global Vaccine and Immunization Research Forum (GVRF), was held in-person for the first time since 2019, with over 450 participants from around the world gathered in Incheon, Republic of Korea to track progress and discuss obstacles related to priority vaccine research and development, to identify gaps, opportunities and actions for the research and development (R&D) community in the areas of vaccines and immunization and to review progress made towards the IA2030 SP7 research and development strategic objectives and goals. The Forum was also an opportunity to present WHO vaccine biomanufacturing training hub in the Republic of Korea to the rest of the world. One of the outcomes was the changing geographical shift towards LMICs in the quality of the science, R&D and manufacturing like for the Republic of Korea and many other counties, in the quality of the epidemiology being done in Africa and in the quality of the regulations in Latin America leading to more equity and justice.

第四届两年一度的全球疫苗和免疫研究论坛（GVRF）自2019年以来首次举行。来自世界各地的450多名与会者齐聚大韩民国仁川，跟踪进展情况并讨论与优先疫苗研发相关的障碍，确定研发（R&D）界在疫苗和免疫领域的差距、机遇和行动，并审查在实现IA 2030 SP 7研发战略目标和目的方面取得的进展。该论坛也是向世界其他地方介绍大韩民国世界卫生组织疫苗生物制造培训中心的机会。结果之一是，在科学、R&D和制造业的质量方面，如大韩民国和许多其他国家，在非洲进行的流行病学的质量方面，以及在拉丁美洲的法规质量方面，地理位置向低收入国家转移，从而导致更加公平和公正。

In the run up to the World Health Assembly, (WHA, 21 – 30 May 2023), we held an information session for Member State representatives on 24 March to brief them on the most pressing vaccine and immunization related issues. Representatives were appraised of the intensification efforts in 2023 ‘Immunization Agenda (IA2030): The global “Big Catch-up" effort’, the multi-partner commitment to both technical and advocacy activation to reverse the unprecedented backsliding in routine immunization coverage and to catch-up those who were missed by immunization programmes during the pandemic period.

在世界卫生大会（2023年5月21日至30日，WHA）召开之前，我们于3月24日为会员国代表举行了一次信息会议，向他们简要介绍了最紧迫的疫苗和免疫接种相关问题。代表们对2023年“免疫议程（IA 2030）：全球“大追赶”努力”中的强化努力进行了评估，这是多伙伴致力于技术和宣传活动，以扭转常规免疫覆盖率前所未有的倒退，并追赶疫情期间免疫方案遗漏的人。

The special efforts, the “Big Catch-up”, are a unique opportunity to assure that every countries’ programme comes out of 2023 on a solid footing, with filling of immunity gaps that ballooned over the pandemic period, and a new trajectory of the immunization programme performance to reduce the number of zero-dose children in every year that follows. It is important to renew global commitments to tackle the surge in cases of diseases such as measles, yellow fever, and polio, including in areas where they had previously been controlled or eliminated.

这种特殊的努力，即“大追赶”，是一个独特的机会，可以确保每个国家的方案在2023年结束时都有一个坚实的基础，填补在大流行期间扩大的免疫缺口，并使免疫方案的绩效有一个新的轨迹，以减少随后每年零剂量儿童的数量。重要的是重新做出全球承诺，应对麻疹、黄热病和脊髓灰质炎等疾病病例的激增，包括在以前控制或消除这些疾病的地区。

The theme for 2023’s WIW is ‘The Big Catch-up', aligned with the 2023 year of intensification. We invite the global immunization community and our key partners to join us next week (24 to 30 April) for WIW under the hashtag #VaccinesWork, as we unite partners and people behind a focused global push to highlight the life-saving importance of vaccines and immunization. Throughout WIW we will highlight successes from countries that have sustained vaccination programmes over the last three years, as well as on newly initiated efforts to scale up vaccinations. WIW is an opportunity to elevate specific asks for priority countries and highlight the barriers to vaccination including conflict and emergencies. We need action everywhere but especially in the 20 countries where over three-quarters of children who missed vaccinations in 2021 live. WIW marks the start of ‘the Big Catch-up', as the year-long push to catch, up, restore and strengthen immunization programmes to surpass the pre-pandemic performance levels.

2023年WIW的主题是“大追赶”，与2023年的强化相一致。我们邀请全球免疫界和我们的主要合作伙伴参加下周（4月24日至30日）在#VaccinesWork标签下举行的WIW，因为我们将合作伙伴和人民团结在一个有重点的全球推动下，以强调疫苗和免疫接种拯救生命的重要性。在整个WIW，我们将重点介绍过去三年来持续实施疫苗接种计划的国家的成功，以及新启动的扩大疫苗接种的努力。WIW是一个提升优先国家具体要求和强调疫苗接种障碍（包括冲突和紧急情况）的机会。我们需要在任何地方采取行动，特别是在20个国家，2021年超过四分之三错过疫苗接种的儿童生活在这些国家。WIW标志着“大追赶”的开始，即长达一年的追赶、追赶、恢复和加强免疫规划的努力，以超过疫情之前的绩效水平。

Please visit the World Immunization Week 2023 where you can find all the social media assets and more information on activities during the week. Take part, join in, and add your voice.

请访问2023年世界免疫周，在那里您可以找到所有社交媒体资产和更多关于该周活动的信息。参与进来，加入进来，加入你的声音。

Looking ahead to the WHA, which will take place from 21 to 30 May 2023, on the immunization front, Members States will be provided with a progress report on “the global road map on defeating meningitis by 2030”, along with a polio update. We are also delighted to announce that our Director General will be hosting a Strategic Round Table on “A safer and healthier tomorrow by restoring essential immunization today “on Friday 26 May at the Palais.

展望将于 2023 年 5 月 21 日至 30 日举行的世界卫生大会，在免疫接种方面，将向会员国提供一份关于 "到 2030 年战胜脑膜炎的全球路线图 "的进展报告，以及小儿麻痹症的最新情况。我们还高兴地宣布，我们的总干事将于5月26日星期五在万国宫主办一次战略圆桌会议，主题是“通过今天恢复基本免疫，创造一个更安全、更健康的明天”。

As we prepare for the upcoming high-level meetings on health in the UN General Assembly, let me take this opportunity to mark WHO’s 75th anniversary. Over the last 75 years, countries of the world have come together as one, through WHO, to advance the ambition of achieving the highest possible standard of human health for everyone, everywhere. Time and again, we have experienced that investing in science lies at the heart of achieving a healthy and prosperous future. WHO has contributed to landmark achievements in public health, including the eradication of smallpox, the near eradication of polio, the expansion of childhood immunization and, more recently, the global response to the COVID-19 pandemic, saving tens upon tens of millions of lives. On this day and every day, let’s commit to achieve Health for All.

在我们筹备即将召开的联合国大会卫生问题高级别会议之际，让我借此机会纪念世界卫生组织成立75周年。在过去75年里，世界各国通过世界卫生组织团结一致，推进为世界各地的每个人实现尽可能高的人类健康标准的雄心。我们一次又一次地体验到，对科学的投资是实现健康和繁荣未来的核心。世界卫生组织为公共卫生领域的里程碑式成就做出了贡献，包括根除天花、几乎根除脊髓灰质炎、扩大儿童免疫接种，以及最近全球应对新冠肺炎疫情，拯救了数千万人的生命。在这一天和每一天，让我们致力于实现人人健康。

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